The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 1980
Filed:
Jun. 24, 1977
Applicant:
Inventors:
Hamao Umezawa, Tokyo, JP;
Takaaki Aoyagi, Fujisawa, JP;
Tomohisa Takita, Asaka, JP;
Rinzo Nishizawa, Tokyo, JP;
Tetsushi Saino, Tokyo, JP;
Assignee:
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A01N / ;
U.S. Cl.
CPC ...
562437 ; 562426 ; 562444 ; 562503 ; 562508 ; 562556 ; 562564 ; 424319 ; 560 20 ; 560 22 ; 560 39 ;
Abstract
Bestatin, which is [(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]-L-leucine, and related compounds which inhibit aminopeptidase B, leucino aminopeptidase and Bleomycin hydrolase, enhance the anti-tumor effect of Bleomycin and exhibit an antifertility effect were synthesized and tested.