The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 1979

Filed:

Aug. 29, 1977
Applicant:
Inventors:

Geoffrey W Grigg, Sydney, AU;

Desmond J Brown, Canberra, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
424251 ; 424253 ; 544265 ; 2602433 ;
Abstract

Purines useful for the potentiation of antibiotics, particularly phleomycin and bleomycin, have the general formula: ##STR1## wherein W is selected from the group consisting of --SRCONR.sup.1 R.sup.2, --SRCN, and --SRCOR.sup.1, in which R is a --(CH.sub.2).sub.n -- group (n is an integer of 1 to 5) which may bear one or more side chain alkyl groups each having from 1 to 5 carbon atoms, and R.sup.1 and R.sup.2, which may be the same or different, are selected from hydrogen atoms and straight or branched chain alkyl groups having from 1 to 5 carbon atoms, or alternatively, R.sup.1 and R.sup.2 together comprise a polymethylene, oxapolymethylene or thiapolymethylene chain containing from 4 to 10 carbon atoms;


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