The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 1979

Filed:

Mar. 01, 1977
Applicant:
Inventor:

Desire J Collen, Winksele, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07G / ; G01N / ; G01N / ;
U.S. Cl.
CPC ...
435-7 ; 2323 / ; 424 12 ; 435180 ; 435803 ; 435 13 ;
Abstract

Antiserum which has been generated against an enzyme-inhibitor-complex is purified by immunoprecipitating a freshly generated antiserum with fresh human bloodplasma to form a precipitate and a fluid, and subjecting the fluid to chromatographic separation over an insolubilized enzyme-inhibitor complex against which the antiserum has been generated. A reagent for immunochemical assay is prepared by contacting the purified antiserum with red bloodcells or synthetic resin particles to obtain on the surface of the red bloodcells or synthetic resin particles antibodies from the antiserum. In a diagnosis test, blood plasma is contacted with the purified antiserum and with red bloodcells or synthetic resin particles which bear the enzyme-inhibitor complex used to prepare the antiserum, and whether or not agglutination occurs is ascertained. In an alternative diagnosis test, blood plasma is contacted with red bloodcells or synthetic resin particles having on their surface antibodies from the antiserum, and whether or not agglutination occurs is ascertained.


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