The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 18, 1979
Filed:
Nov. 06, 1978
Applicant:
Inventors:
Egidio Marchi, Bologna, IT;
Lauretta Montecchi, Bologna, IT;
Assignee:
Alfa Farmaceutici, S.p.A., Bologna, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
2602 / ; 424244 ;
Abstract
A process is disclosed for the preparation of 3 iodo-3 bromorifamycin S which consists in reacting rifamycin S with at least 2 equivalents of the corresponding halogen in the presence of at least one mole of pyridine for each equivalent of halogen. The reaction is carried out in inert, polar, hydrofillic solvents at a temperature not above the room temperature. The yields are very high and the products obtained have a high degree of purity.