The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 1979

Filed:

Dec. 27, 1977
Applicant:
Inventors:

Gilbert Regnier, Chatenay-Malabry, FR;

Roger Canevari, Elancourt, FR;

Michel Laubie, Vaucresson, FR;

Jean-Claude Poignant, Bures sur Yvette, FR;

Assignee:

Science Union et Cie, Suresnes, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
424250 ; 544366 ; 544367 ;
Abstract

Disubstituted piperazines of the formula: ##STR1## wherein: ##STR2## is naphthyl, benzo [b] furanyl, benzo [b] thienyl, benzodioxolyl, benzodioxanyl, benzodioxacycloheptanyl, coumaranyl, chromanyl, .DELTA..sup.3 -chromenyl, thiochromanyl or .DELTA..sup.3 -thiochromenyl, X is nitrogen and simultaneously Y is oxygen or sulfur, or X is sulfur, imino (NH) or methylimino (N CH.sub.3) and simultaneously Y is nitrogen, and R is hydrogen, lower alkyl, phenyl, halophenyl, lower-alkylphenyl or lower alkoxyphenyl. These compounds possess interesting pharmacological and therapeutic properties, and may be used as medicines, especially in the treatment of hypertension, peripheral vascular disorders and Parkinson's disease.


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