The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 1979
Filed:
May. 19, 1978
Applicant:
Inventors:
F Aileen Bouffard, Scotch Plains, NJ (US);
Burton G Christensen, Metuchen, NJ (US);
Nathan G Steinberg, Plainfield, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
424274 ; 2602452 ; 2603 / ; 26032625 ; 424250 ; 424251 ; 424263 ; 424269 ; 424270 ; 424272 ; 4242 / ; 542416 ; 544239 ; 544316 ; 544355 ; 546272 ; 548336 ;
Abstract
Disclosed are Schiff's base derivatives of the antibiotic thienamycin, which has the following structure: ##STR1## Such compounds and their pharmaceutically acceptable salt, ester and amide derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such derivatives, pharmaceutical compositions comprising such derivatives, and methods of treatment comprising administering such derivatives and compositions when an antibiotic effect is indicated.