The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 1979
Filed:
Feb. 21, 1978
Applicant:
Inventors:
Michel Biollaz, Basel, CH;
Jaroslav Kalvoda, Binningen, CH;
Assignee:
Ciba-Geigy Corporation, Ardsley, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J / ; C07J / ; C07J / ;
U.S. Cl.
CPC ...
2602 / ; 26039745 ; 2603975 ;
Abstract
11,12-Unsaturated 9.alpha.-fluorosteroids comprising a new class of steroid compounds are obtained by a novel process, wherein a corresponding 9.alpha.-fluoro-11.beta.-hydroxysteroid is dehydrated with a reagent of the formula F.sub.3 SX in which X denotes an amino group derived from a secondary amine. Of a particular interest among the products of the invention are compounds of the general formula IB ##STR1## in which the symbols R.sub.5 -R.sub.10 have the meanings given hereinafter; such compounds are especially useful as analogues of cortical hormones possessing antiinflammatory activity.