The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 1979

Filed:

Oct. 21, 1977
Applicant:
Inventors:

Shosuke Okamoto, Tarumi-ku, Kobe-shi, Hyogo, JP;

Ryoji Kikumoto, Machida, JP;

Yoshikuno Tamao, Yokohama, JP;

Kazuo Ohkubo, Machida, JP;

Shinji Tonomura, Tokyo, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
424244 ; 2601 / ; 2602 / ; 2602 / ; 2602 / ; 26032633 ; 26050112 ; 26050114 ; 2605 / ; 424177 ; 424267 ; 424274 ; 424316 ; 424321 ; 546205 ;
Abstract

N.sup.2 -naphthalenesulfonyl-L-arginine amides having the formula ##STR1## or the acid addition salts thereof with a pharmaceutically acceptable acid wherein R.sub.1 is alkenyl of not more than 10 carbon atoms, or substituted alkyl containing not more than 20 carbon atoms wherein said substituent is a member selected from the class consisting of alkoxy, alkoxycarbonyl, arylcarbamoyl acyl, acyloxy, N,N-polymethylenecarbamoyl and carboxy, and R.sub.2 is aryl, cycloalkyl, aralkyl or cycloalkylalkyl, respectively containing not more than 15 carbon atoms and R' is 1-naphthyl substituted with a member selected from the class consisting of 2-dialkylamino, 3-dialkylamino, 4-dialkylamino, 6-dialkylamino, 7-dialkylamino, 8-dialkylamino, respectively containing not more than 20 carbon atoms, and 5-dialkylamino containing 3-20 carbon atoms; or 2-naphthyl substituted with dialkylamino containing not more than 20 carbon atoms.


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