The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 1979
Filed:
Nov. 16, 1977
Daniel B Wagner, Jerusalem, IL;
Zvi Gross, Jerusalem, IL;
Ames-Yissum Ltd., Jerusalem, IL;
Abstract
A specific binding assay method and test kit for determining a ligand, particularly an antigen or hapten, in, or the ligand binding capacity of, a liquid medium, particularly a body fluid such as serum, wherein the liquid medium is combined with assay reagent means including a labeled binding component, such as a radiolabeled form of the ligand, with the improvement that separation of the resulting bound-species and free-species of the labeled component is accomplished by selectively adsorbing the free-species onto a solid comprising a nonion-exchange cross-linked styrene polymer. The method is particularly suited to the radioimmunoassaydetection of nonproteinaceous haptens such as thyroxine, triiodothyronine, estriol, vitamin B.sub.12 and digoxin. The styrene polymer adsorbent provides a very effective and readily available separation means for use in specific binding assays.