The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 1979
Filed:
Sep. 21, 1977
Serge J Bonfils, Paris, FR;
Juliette M Dubrasquet, Paris, FR;
Pierre Fromageot, Versailles, FR;
Jean P Girma, Gif sur Yvette, FR;
Miguel Lewin, Asnieres, FR;
Jean L Morgat, Paris, FR;
Commissariat a l'Energie Atomique, Paris, FR;
Institut National de la Sante et de la Recherche Medicale, Paris, FR;
Abstract
The present invention relates to a method of treating diseases and particularly gastroduodenal ulcers linked to an hypersecretion of gastrin, and to polypeptide amide derivatives which can be used in this method as therapeutic agents and more specifically as antagonists of the action of gastrin and related polypeptides relative to their specific biological receptors. This method comprises administering a therapeutically effective amount of a polypeptide amide derivative of general formula: ##STR1## in which R.sub.1 represents a hydrogen atom or an acyl radical and R.sub.2 represents a substituted or unsubstituted aryl radical e.g. nitrophenyl group or dinitrophenyl group such as 2-nitrophenyl or 2-4-dinitrophenyl.