The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 1979
Filed:
Jun. 17, 1977
Murray J Sanders, Delray Beach, FL (US);
Other;
Abstract
A method for proving the potency and atoxicity of modified neurotoxin is provided. A thin sheet of viable cells is provided on a growth substrate. Viability of the sheet of cells is defined as exhibiting an uninhibited growth potential of at least 10.sup.6 Plaque Forming Units of Semliki Forest virus. The sheet of cells is treated with the test modified neurotoxin and then inoculated with the Semliki Forest virus. The reduction in the number of plaques of Semliki Forest virus in the culture indicates the potency of the modified neurotoxin, since the modified neurotoxin interferes with plaque formation by the Semliki Forest virus in proportion to its potency. Atoxicity of the modified neurotoxin is demonstrated by lack of cell destruction.