The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 1979

Filed:

Sep. 06, 1977
Applicant:
Inventors:

Shigeshi Toyoshima, Tokyo, JP;

Mie Itoh, Tokyo, JP;

Syosuke Yamamura, Nagoya, JP;

Yoshiko Seto, Funabashi, JP;

Haruhisa Fujita, Kamakura, JP;

Mariko Fukuma, Musashino, JP;

Mikiro Fujiwara, Tokyo, JP;

Munemoto Itoh, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12D / ; C07G / ;
U.S. Cl.
CPC ...
424115 ; 195 96 ;
Abstract

A process for preparing an antimalignant agent which comprises cultivating Staphylococcus epidermidis STF (Bikoken(or Microbic Industry Technological Institute)Deposit No. 3706; ATCC 31310) in a liquid culture medium, removing solid matter from the culture solution, concentrating the remaining solution, washing the precipitate thus formed with water, re-dissolving the precipitate, fractionating the solution into a number of fractions by an adsorptive filtration gel or the molecular sieve method, taking a fraction exhibiting antimalignant activity, concentrating the fraction, further purifying the fraction by ion-exchange chromatography and separating the active ingredient; and the antimalignant agent thus obtained.


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