The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 1979
Filed:
Sep. 27, 1976
Applicant:
Inventors:
Ronald P Pelley, Cleveland, OH (US);
Kenneth S Warren, Cleveland Heights, OH (US);
Assignee:
Edna McConnell Clark Foundation, New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
424-1 ; 424-9 ; 424 88 ;
Abstract
Schistosoma mansoni eggs are ground to liberate soluble egg antigens which are fractionated and purified by absorption, gel filtration and/or ion exchange chromatography, and then radioactively labelled with .sup.125 I. A fraction, identified as MSA.sub.1, is specific to the mature egg stage of Schistosoma mansoni and thus can be used to detect the presence of antibody to mature Schistosoma mansoni eggs in a patient's serum even as compared with mature eggs of different Schistosoma (species specific) or of Schistosoma mansoni worms but not mature eggs (stage specific).