The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 1979

Filed:

May. 18, 1978
Applicant:
Inventors:

Ronnie R Crenshaw, Dewitt, NY (US);

George M Luke, LaFayette, NY (US);

Assignee:

Bristol-Myers Company, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ;
U.S. Cl.
CPC ...
2605 / ; 2605 / ;
Abstract

Anti-ulcer agents of the formula ##STR1## wherein R.sup.1 is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive, are prepared by reacting a compound of the formula ##STR2## wherein X is a conventional leaving group, preferably in the form of its acid addition salt, with a compound of the formula ##STR3## wherein R.sup.1 is as defined above. The intermediates of Formula III may be prepared by reacting a cysteamine salt with an isothiourea of the formula ##STR4## wherein R.sup.1 is as described above, in the presence of a base.


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