The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 1979

Filed:

Feb. 13, 1978
Applicant:
Inventors:

Edward D Brown, Macclesfield, GB;

Walter Hepworth, Macclesfield, GB;

Ian T Kay, Wokingham, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
424249 ; 544194 ; 544211 ;
Abstract

The invention concerns pharmaceutical compositions having analgesic, and in some cases, in addition anti-inflammatory properties, for use in the treatment of painful inflammatory joint disease, which compositions contain as active ingredient a new or old 1-alkyl (or cycloalkyl)-4-(N-alkanoyl)substituted-amino-tetrahydro-1,3,5-triazine-2,6- dione of the formula: ##STR1## or a base-addition salt thereof. Many of the compounds of formula I are previously known as herbicides, and a representative example of such a compound which has now been surprisingly found to have useful analgesic properties is 1-isopropyl-4-(N-acetyl)isopropylamino-tetrahydro-1,3,5-triazine-2,6-dione . However certain of the compounds of formula I and the base-addition salts thereof are novel, a representative example being 1-isopropyl-4[(N-acetyl)pent-3-ylamino]-tetrahydro-1,3,5-triazine-2,6-dion e, and are provided as a further feature of the invention, together with analogy processes for their manufacture.


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