The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 1979
Filed:
Mar. 04, 1976
Richard A Harte, Redwood City, CA (US);
International Diagnostic Technology, Inc., Santa Clara, CA (US);
Abstract
A body suitable for use in the quantitative detection of an unknown quantity of a biologically derived sample suitably by radioimmunoassay, fluorometric detection, or by spectrophotometry. The body includes a handle attached to a nonparticulate, nonswellable, impermeable continuous surface region. A diagnostic reagent (e.g., an antibody) is covalently attached to the surface region. The surface region is stirred by the handle in a solution of sample substance (e.g., antigen) for reaction with the diagnostic reagent. In a competitive binding technique, a labelled substance (e.g., fluorochrome labelled antigen) is simultaneously contacted with the sample. Thereafter, the surface region is washed, and the label is measured as by a fluorometer. The technique is also applicable to the so-called 'sandwich technique' in which the labelled substance (e.g., labelled antibody) is reacted with the sample substance after it has been reacted with the diagnostic reagent. The above type of surface facilitates simple and effective separation of bound from free labelled substance and allows thorough washing to cleanse the surface of residual free and non-specifically bound labelled substance.