The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 1978
Filed:
Dec. 16, 1976
Hideo Fukushima, Saitama, JP;
Yoshikuni Suzuki, Kawagoe, JP;
Nisshin Flour Milling Co., Ltd., Tokyo, JP;
Abstract
Isocarbostyrils of the formula ##STR1## wherein R.sub.1 represents a lower alkyl group having 1 to 4 carbon atoms, and R.sub.3 and R.sub.4, same or different, individually means hydrogen or an alkyl, aralkyl or cycloalkyl group provided at least either one of R.sub.3 and R.sub.4 should not be hydrogen, or R.sub.3 and R.sub.4 together with the adjacent nitrogen atom may form a heterocyclic ring, having anti-arrhythmic activity and low toxicity are prepared by reacting a 4-substituted isocarbostyril derivative of the formula ##STR2## wherein R.sub.1 is the same as defined above and R.sub.2 represents ##STR3## or its functional equivalent, e.g. --Ch.sub.2 --CH(OH)CH.sub.2 X in which X represents a halogen atom, with an alkyl amine of the general formula ##STR4## wherein R.sub.3 and R.sub.4 are same as defined above..