The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 1978
Filed:
Dec. 07, 1976
Applicant:
Inventors:
Istvan Turcsan, Budapest, HU;
Istvan Jelinek, Budapest, HU;
Jozsef Ugrics, Budapest, HU;
Istvan Csik, Budapest, HU;
Eva Somfai, Budapest, HU;
Iren Csaszar nee Toth, Budapest, HU;
Assignee:
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara RT, Budapest, HU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
542449 ; 546144 ; 2604 / ; 2605 / ;
Abstract
In the production of perparine or papaverine and their hydrochlorides, the formation of impurities in the reaction mixture is suppressed by fractionating a 3,4-di-R-benzyl-cyanide in the presence of an organic base (e.g. pyridine, dimethylformamide, ethylenediamine or triethylamine) followed by hydrogenation with a Raney-nickel catalyst treated with aqueous ammonium carbonate solution. R is methoxy or ethoxy.