The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 1978
Filed:
Aug. 01, 1977
Applicant:
Inventors:
Norman W Bristow, Wollaton, GB;
Peter E Macey, Nottingham, GB;
Kenneth J Nichol, West Bridgford, GB;
Malcolm F Sim, Woodborough, GB;
Assignee:
The Boots Company Limited, , GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
424250 ; 424246 ; 42424856 ; 544 51 ; 544 52 ; 544 58 ; 544 62 ; 544105 ; 544116 ; 544237 ; 544235 ; 260154 ; 260155 ; 260157 ; 260165 ; 260152 ; 260158 ; 260162 ; 544353 ; 544283 ;
Abstract
Therapeutic activity, and in particular the ability to induce diuresis or saluresis, has been discovered in 4-hydroxy- or 4-mercapto-2-aryl-1,2-dihydrophthalazine-1-acetic acids, the tautomers of these namely 4-oxo or thio-2-aryl-1,2-tetrahydrophthalazine-1-acetic acids, and in the ester and alcohol derivatives of the acids, and in the acyl derivatives of the 4-hydroxy or mercapto compounds and in the 3-alkyl derivatives of the 4-oxo or thio compounds. Therapeutic compositions and methods using the compounds are described, as also are novel compounds.