The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 1978

Filed:

Sep. 19, 1977
Applicant:
Inventors:

Ta Sen Chou, Indianapolis, IN (US);

Gary D Zintgraff, Indianapolis, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
544 20 ;
Abstract

Passing a solution, buffered to a pH of from about 3.5 to about 4.5, of an alkali metal or ammonium salt of cefamandole through a bed of an adsorbent resin depending on van der Waals forces for adsorption followed by acidification to a pH of about 2.0 with a non-oxidizing inorganic acid yields pure crystalline cefamandole, which can be separated and dried, or partitioned into a preferential solvent from which crystalline sodium cefamandole can be recovered.


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