The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 1978
Filed:
Mar. 29, 1976
Applicant:
Inventors:
Yoshiaki Kamano, Tokyo, JP;
Kazuhiko Michishita, Saitama, JP;
Teruya Seki, Tokyo, JP;
Ichiro Tanaka, Tokyo, JP;
Assignee:
Taisho Pharmaceutical Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J / ;
U.S. Cl.
CPC ...
26039745 ; 2602 / ;
Abstract
One-step method for preparing 17 .alpha.-ester-21-halo pregnanes by reacting 17 .alpha., 21-cyclic orthoesters of 17 .alpha., 21-dihydroxy pregnanes with a halo compound in the presence of an organic polar solvent, simultaneously resulting in halogenation at 21-position and esterification at 17 .alpha.-position of said 17 .alpha., 21-cyclic orthoesters, the reaction proceeding in a short period of time without, or substantially without, any unfavorable side-reactions.