The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 1978
Filed:
Apr. 13, 1977
Applicant:
Inventors:
Graham J Durant, Welwyn Garden City, GB;
Charon R Ganellin, Welwyn Garden City, GB;
Torben Hesselbo, North Berwick, GB;
George R White, Harpenden, GB;
Assignee:
Smith Kline & French Laboratories Limited, Welwyn Garden City, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
424263 ; 2602 / ; 2602 / ; 2602 / ; 548336 ; 4242 / ;
Abstract
The compounds are heterocyclomethylsulphinylethyl derivatives of N-cyanoguanidines, thioureas and 2-amino-1-nitroethylene which are histamine H.sub.2 -antagonists or are converted into histamine H.sub.2 -antagonists in the animal body. Two specific compounds of the present invention are 1-nitro-2-[2-((2-thiazolyl)methylsulphinyl)ethylamino]-2-[2-((2-thiazolyl) methylthio)ethylamino]ethylene and 1-nitro-2,2-bis-[2-((2-thiazolyl)methylsulphinyl)ethylamino]ethylene.