The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 1978

Filed:

Jun. 03, 1977
Applicant:
Inventors:

James S Kaltenbronn, Ann Arbor, MI (US);

Theodore H Haskell, Ann Arbor, MI (US);

Leonard Doub, Ann Arbor, MI (US);

Assignee:

Warner-Lambert, Morris Plains, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
424266 ; 424246 ; 2602391 ; 544 21 ; 544 25 ; 544 27 ; 544 28 ; 544 24 ; 544 26 ; 544 30 ;
Abstract

Novel organic amide compounds which are N-[6-[(aminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinyl]penicillin and cephalosporin type compounds having broad spectrum antibacterial utility are provided by (a) reacting the free amino acid of the appropriate penicillin or cephalosporin or the acid salt or silylated derivative or complex thereof with a reactive derivative of the corresponing N-6-[(aminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinic acid or (b) reacting the free amino acid 6-aminopenicillanic acid, 7-aminocephalosporanic acid, 7-amino-3-methylceph-3-em-4-carboxylic acid or a related compound or the acid salt or silylated derivative thereof with a reactive derivative of the corresponding D-N-[6-[(aminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinyl]-2-substituted glycine. Pharmaceutical compositions containing said compounds and methods for treating infections using said compositions are also disclosed.


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