The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 1978
Filed:
Feb. 17, 1977
Applicant:
Inventors:
Hamao Umezawa, Tokyo, JA;
Tomio Takeuchi, Tokyo, JA;
Akira Takamatsu, Yokohama, JA;
Kenji Kayahara, Yokohama, JA;
Assignee:
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai, Tokyo, JA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424230 ;
Abstract
Compounds having the general formula ##STR1## wherein R.sup.2 is substituted either at the 4'-position or at the 5'-position and is hydrogen, fluoro, bromo, chloro, hydroxy or lower alkyl; R.sup.3 is chloro, bromo or lower alkyl; R.sup.4 is hydroxy, amino or lower alkoxy, and Z is hydrogen or lower alkyl and the nontoxic, pharmaceutically acceptable metal salts of said compounds when Z is hydrogen exhibit strong activities in inhibiting histidine decarboxylase and anthine oxidase.