The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 1978
Filed:
Jun. 23, 1975
Applicant:
Inventors:
Paul Buchschacher, Arlesheim, CH;
Andor Furst, Basel, CH;
Ludwig Labler, Allschwil, CH;
Werner Meier, Bottmingen, CH;
John William Scott, Upper Montclair, NJ (US);
Assignee:
Hoffmann-La Roche, Inc., Nutley, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
2603 / ; 260338 ; 2603 / ; 2603 / ; 2603407 ; 2605 / ; 2605 / ;
Abstract
Treatment of de-A steroids with a methylation agent at extremely low temperatures, i.e., below -50.degree. C. produces corresponding 10.beta.-methyl-.DELTA..sup.9(11) -deA steroids with a high 10.beta. to 10.alpha. isomer ratio. A number of the product 10.beta.-methyl-.DELTA..sup.9(11) -deA steroids are novel compounds. They are useful as intermediates in the synthesis of known medicinally valuable steroids.