The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 1978
Filed:
Nov. 08, 1976
Eva Borowski, Radebeul, DL;
Klaus Braun, Radebeul, DL;
Klaus Breuel, Dresden, DL;
Christoph Dauth, Radebeul, DL;
Dieter Erge, Halle, DL;
Werner Grawert, Radebeul, DL;
Detlev Groger, Halle, DL;
Liselotte Hohne, Dresden, DL;
Edda Knothe, Radebeul, DL;
Monika Muller, Radebeul, DL;
Gisela Nordmann, Dresden, DL;
Rudolf Schirutschke, Radebeul, DL;
Klaus-Dieter Volzke, Dresden, DL;
VEB Arzneimittelwerk Dresden, Radebeul, DL;
Abstract
Ergoline derivatives including alkaloids and 9,10-dihydroalkaloids of the ergotoxine group and including ergometrine are made by forming a submerged culture under aerobic conditions by inoculation of an aqueous medium containing a carbon source, an organic or inorganic nitrogen source or both of these sources, and nutrient salts, the inoculum being spores obtained from a strain of Claviceps purpurea (Fr.) Tul. deposited under number IMET PA 130, and then, after completion of the cultivation, extracting the formed alkaloids from the culture and, if necessary, 9,10-dihydrogenating the extracted alkaloids, and converting the alkaloids into pharmaceutically acceptable acid addition salts.