The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 1978
Filed:
Sep. 24, 1976
Arkady Mikhailovich Likhosherstov, Moscow, SU;
Liya Semenovna Nazarova, Moscow, SU;
Alexandr Petrovich Skoldinov, Moscow, SU;
Galina Alexandrovna Markova, Moscow, SU;
Natalya Veniaminovna Kaverina, Moscow, SU;
Other;
Abstract
Novel compounds 10'-[.omega.-N/1,4-diazabicyclo(4,m,0)-alkanyl/-acyl] -phenothiazines having the formula: ##STR1## wherein X = H, Cl, CF.sub.3 ; n = 1, 2, 3; m = 3, 5; and their salts of acidic addition and quaternary salts. The process for producing said compounds comprises reacting .omega. -chloracyl -2-substituted phenothiazines with 1,4-diazabicyclo(4,m,0)-alkanes in an inert solvent medium at a temperature of 50-140.degree. C followed by isolation of the desired product. Said compounds are pharmacologically active. The most active compound 10'- [.beta.-N-/1,4-diazabicyclo-(4,3,0)-nonanyl/-propyonyl]-2'-chlorophenothia zine of the formula: ##STR2## is an active principle of a medicated compound possessing spasmolytic and coronary-dilatant effect.