The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 1978
Filed:
Nov. 25, 1974
Erich Schacht, Darmstadt, DT;
Werner Mehrhof, Darmstadt, DT;
Zdenek Simane, Darmstadt, DT;
Herbert Nowak, Darmstadt, DT;
Detlev Kayser, Darmstadt, DT;
Merck Patent Gesellschaft mit beschrankter Haftung, Darmstadt, DT;
Abstract
Hydratropic acid derivatives of the formula ##STR1## wherein R.sub.1 is H, alkyl of 1-4 carbon atoms, 2-acetamidoethyl, 1-methyl-4-piperidyl, or 2,3-dihydroxypropyl, and R.sub.2 is Hal, phenyl, 4-Hal-phenyl, 4-Hal-phenoxy, 4-Hal-phenoxymethyl, 1,2,3,4-tetrahydro-1-naphthyl, 1-pyrryl, piperidino, isoindolino, 1,2,3,4-tetrahydroquinolino, 1,2,3,4-tetrahydro-4-quinolyl or 1-methyl-1,2,3,4-tetrahydro-4-quinolyl, Hal being F, Cl, or Br, and the physiologically acceptable salts thereof, which possess cholesterol and triglyceride serum-level-lowering activity, can be prepared by reacting a phenol of the formula ##STR2## with a compound of the formula X--C(CH.sub.3)(C.sub. 6 H.sub.5)--COOR.sub.1 wherein X represents Cl, Br, I, OH, or esterified OH.