The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 1978
Filed:
Apr. 15, 1974
Applicant:
Inventors:
Linneaus C Dorman, Midland, MI (US);
Edwin C Steiner, Midland, MI (US);
Assignee:
The Dow Chemical Company, Midland, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ;
U.S. Cl.
CPC ...
2601 / ; 260349 ; 560158 ;
Abstract
The preparation of the azide of a carboxylic acid by reacting the hydrazide of the acid with nitrous acid is facilitated by using the organic solvent-soluble complex of an alkali metal nitrite with an ethylene oxide or propylene oxide cyclic polymer as the nitrous acid source. The improvement is particularly useful as a means for making peptides by the coupling reaction of an amino acid ester or other derivative with an acid azide in an anhydrous reaction medium.