The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 1977
Filed:
Jun. 03, 1976
Applicant:
Inventors:
Hartmut Ertel, Kelkheim, Taunus, DT;
Gunther Heubach, Kelkheim, Taunus, DT;
Erhard Wolf, Hofheim, Taunus, DT;
Assignee:
Hoechst Aktiengesellschaft, Frankfurt am Main, DT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07C / ; C07D / ;
U.S. Cl.
CPC ...
424282 ; 2603 / ; 2603 / ; 2604 / ; 2605 / ; 424304 ;
Abstract
A 2-hydroxyethylidene-cyano acetic acid anilide is prepared by heating an acetoacetic acid anilide with an orthoformic acid ester and acetic anhydride, isolating the resulting 2-alkoxymethylene-acetoacetic acid anilide and treating it with hydroxylamine and the isoxazole so obtained with a base, and optionally reacting the resulting alkali metal or ammonium salt with a mineral acid or a strong organic acid. The compounds of the invention have anti-inflammatory and analgesic activity.