The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 1977

Filed:

Aug. 18, 1976
Applicant:
Inventors:

Charles E Coverdale, Portage, MI (US);

Louis L Skaletzky, Kalamazoo, MI (US);

Assignee:

The Upjohn Company, Kalamazoo, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424250 ;
Abstract

Novel compounds of the formula: ##STR1## are disclosed with the corresponding hydrates and pharamceutically acceptable acid addition salts thereof, wherein R.sub.1 is halogen, lower alkyl, or trifluoromethyl; R.sub.2 is lower alkyl, substituted or unsubstituted phenyl or benzyl and R.sub.3 is hydrogen. The novel compounds are useful for the treatment of hypertension and anxiety in mammals, including humans. Disclosed also are compositions containing the novel compounds of the invention and methods of their use in the treatment of hypertension and anxiety.


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