The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 1977

Filed:

Jul. 21, 1975
Applicant:
Inventors:

Gerald L Maurer, Fairfield, OH (US);

Sudhir K Shringarpurey, Cincinnati, OH (US);

Assignee:

National Research Laboratories, Cincinnati, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N / ;
U.S. Cl.
CPC ...
424294 ; 424289 ; 424290 ; 424291 ; 424292 ; 424295 ; 424296 ; 424287 ;
Abstract

Antimicrobial agents are disclosed containing as the active ingredient a metal complex of a metal ion and a polyfunctional organic ligand. The antimicrobial metal complexes are characterized by a very unexpected aqueous proton induced dissociation property which causes the controlled release of toxic metal ion at a pH compatible with microorganism growth. This dissociation property is represented by a sigmoidally shaped curve, i.e., one curved in two different directions like the letter 'S,' on a cartesian coordinate plot of the negative logarithm (log) of metal ion concentration versus the negative logarithm (log) of hydrogen ion concentration (or otherwise known as a pM-pH diagram). Antimicrobial metal complexes are also disclosed which are extremely effective in the controlled release of metal ion from the complex in about the normal range of physiological pH, i.e., about 10.sup.- 4 to 10.sup.-9 moles of hydrogen ion per liter.


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