The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 1977

Filed:

Nov. 29, 1974
Applicant:
Inventors:

Ulrich Kerb, Berlin, DT;

Rudolf Wiechert, Berlin, DT;

Klaus Kieslich, Berlin, DT;

Karl Petzoldt, Berlin, DT;

Helmut Wachtel, Berlin, DT;

Dieter Palenschat, Berlin, DT;

Reinhard Horowski, Berlin, DT;

Gert Paschelke, Berlin, DT;

Wolfgang Kehr, Berlin, DT;

Assignee:

Schering Aktiengesellschaft, Berlin & Bergkamen, DT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N / ; A61K / ; C07C / ;
U.S. Cl.
CPC ...
424303 ; 260400 ; 260405 ; 2604 / ; 2604 / ; 2604 / ; 2604 / ; 260483 ; 2605 / ; 424308 ; 424311 ; 424312 ; 424313 ; 424331 ;
Abstract

D-homo-20-ketopregnanes of the formula ##STR1## wherein R.sub.1 is oxygen, ##STR2## in which R.sub.5 is hydrogen or lower acyl; R.sub.2 is hydrogen or methyl; R.sub.3 is oxygen, ##STR3## or two hydrogen atoms; R.sub.4 is hydrogen, hydroxy or acyloxy; R.sub.6 is hydrogen or methyl; and R.sub.7 is hydrogen, acetyl, hydroxy or lower acyloxy in the .alpha.- or .beta.-position possess CNS-depressant activity, including anesthesia upon parenteral administration, and are produced by hydrogenating the corresponding steroids having double bonded C.sub.5 and/or C.sub.16 carbon atoms.


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