The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 1977
Filed:
Jul. 16, 1975
Ryozo Maeda, Osaka, JA;
Katsumi Hirose, Kishiwada, JA;
Shionogi & Co., Ltd., Osaka, JA;
Abstract
Thiazole derivatives represented by the general formula: ##STR1## wherein A is oxygen, sulfur, imino, or NR.sub.3, wherein R.sub.3 is C.sub.1.sub.-5 alkyl, C.sub.2.sub.-5 alkenyl, C.sub.3.sub.-5 alkynyl, C.sub.3.sub.-6 cycloalkyl-C.sub.1.sub.-3 alkyl or C.sub.7.sub.-8 aralkyl; R.sub.1 is hydrogen, C.sub.1.sub.-5 alkyl, C.sub.2.sub.-5 alkenyl, C.sub.3.sub.-5 alkynyl, C.sub.3.sub.-6 cycloalkyl-C.sub.1.sub.-3 alkyl or C.sub.7.sub.- 8 aralkyl; R.sub.2 is hydroxy, C.sub.1.sub.-5 alkoxy or OM, wherein M is alkali metal, or one equivalent of alkaline earth metal, cupric or aluminum cation; n is an integer of 0 or 1; X.sub.1 and X.sub.2 are independently hydrogen or C.sub.1.sub.-5 alkyl; Y.sub.1 and Y.sub.2 are independently hydrogen, halogen, C.sub.1.sub.-5 alkyl, C.sub.1.sub.-5 alkoxy or trifluoromethyl; and the group ##STR2## is linked to one of the meta or para positions of the benzene ring A, n is not 0 when A is imino and --CH.sub.2 --COR.sub.2 does not substitute the thiazole ring when A is imino, being useful as anti-inflammatory, anti-rheumatic, analgesic or anti-lipemia agents.
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