The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 1977
Filed:
Aug. 25, 1975
Applicant:
Inventors:
Larry R Lappi, Stillwater, MN (US);
Edward H Erickson, Woodbury, MN (US);
Assignee:
Riker Laboratories, Inc., Northridge, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
2602 / ; 2603305 ; 260332 ; 2604 / ; 260578 ; 424258 ;
Abstract
4-Hydroxy[1]benzothieno[3,2-f]quinoline-2-carboxylic acids and esters thereof are prepared by the reaction of an optionally substituted 2-aminobenzothiophene with dimethyl acetylenedicarboxylate followed by ring closure. The sulfur atom of the intermediate compounds in the process can be oxidized to oxide or dioxide state, then hydrolyzed to the acids, or first hydrolyzed to the acids and then oxidized, if desired. The acids are physiologically active as anti-allergic agents in the acid form or as salts.