The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 1977

Filed:

Jul. 12, 1974
Applicant:
Inventors:

Thomas Raabe, Heusenstamm, DT;

Josef Scholtholt, Frankfurt am Main, DT;

Rolf-Eberhard Nitz, Bergen-Enkheim, DT;

Assignee:

Cassella Farbwerke Mainkur Aktiengesellschaft, Frankfurt am Main-Fechenheim, DT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
2602 / ; 424263 ; 2602 / ; 2602 / ; 2602 / ; 2602 / ; 2602 / ; 2603 / ; 2603 / ; 2605 / ; 2605 / ; 2605 / ; 2605 / ; 2605 / ;
Abstract

The present invention relates to pharmacologically valuable new derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production. The new derivatives of 1-phenoxy-3-amino-propane-2-ol are suitable for the treatment and prophylaxis of diseases of the heart. Some possess pronounced .beta.-adrenalytic or anti-arythmic properties. These new derivatives have the structural formula ##STR1## wherein X signifies ##STR2## and the phenyl nucleus I may be mono-, di- or trisubstituted by alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, alkoxy, alkenyloxy, phenyl, halogen or the radical --NR.sub.1 R.sub.2, in which R.sub.1 stands for alkyl or acyl and R.sub.2 for hydrogen or alkyl, together with their aldehyde condensation products and their acid addition salts.


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