The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 1977

Filed:

May. 28, 1975
Applicant:
Inventors:

Ernst Habicht, Oberwil, CH;

Hans Kuhnis, Basel, CH;

Assignee:

Ciba-Geigy Corporation, Ardsley, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
424266 ; 2602 / ; 2602 / ; 2602 / ; 2602 / ; 26029369 ; 2602 / ; 2602949 ; 2602 / ; 424267 ;
Abstract

The present invention relates to 1,4-dihydropyridines of the formula I ##STR1## and their tautomers, wherein R.sub.1 represents an aryl radical, R.sub.2 and R.sub.3 independently of one another represents hydrogen or a hydrocarbon radical, R.sub.4 represents an alkyl, aryl or aralkyl radical, R.sub.5 denotes an alkoxy radical, which is optionally substituted by an amino group, or denotes an amino group and n is 1 or 2, especially to the 2,6-dimethyl-3-carbomethoxy-5-methylsulphonyl-4-(2-trifluoromethylphenyl)- 1,4-dihydro-pyridine and to the 2,6-dimethyl-3-carbomethoxy-5-methylsulphonyl-4-(2-nitrophenyl)-1,4-dihydr opyridine. They have an antihypertensive activity.


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