The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 1977

Filed:

May. 14, 1975
Applicant:
Inventors:

Alexander U Bertland, Lansdale, PA (US);

Alfred A Tytell, Lansdale, PA (US);

George P Lampson, Hatfield, PA (US);

Eugene Buynak, North Wales, PA (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C12K / ; C12K / ;
U.S. Cl.
CPC ...
195-14 ; 195-15 ; 424 89 ;
Abstract

Hepatitis B antigen useful as vaccine is prepared from clarified plasma of hepatitis B donors by treating with pepsin at a pH wherein pepsin is enzymatically active, treating with urea, and optionally treating with formaldehyde.


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