The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 1977
Filed:
Jul. 16, 1975
Applicant:
Inventors:
Rodney Ian Fryer, North Caldwell, NJ (US);
Robert Ye-Fong Ning, West Caldwell, NJ (US);
Leo Henryk Sternbach, Upper Montclair, NJ (US);
Armin Walser, West Caldwell, NJ (US);
Assignee:
Hoffmann-La Roche Inc., Nutley, NJ (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
2602 / ; 2602 / ; 2602 / ; 2602 / ; 2602 / ; 2602 / ; 2602 / ; 2602 / ; 2602 / ; 2603 / ; 26032614 ; 424250 ; 424258 ; 42424856 ; 42424857 ; 42424858 ;
Abstract
Derivatives of 7H-indolo[2,3-c]quinolin-6(5H)-one and 7H-indolo[2,3-c]quinoline, prepared, inter alia, from the corresponding 3-azido-4-phenylcarbostyrils or corresponding N-(lower alkylamino)-3-(2-fluorophenyl)-indole-2-carboxamides, are described. The end products of the invention are useful as anti-tumor agents, i.e., they inhibit the growth of transplantable tumors.