The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 1977
Filed:
Jul. 03, 1975
Applicant:
Inventor:
Riaz F Abdulla, Greenfield, IN (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
2602 / ; 2602 / ; 2605 / ; 71 92 ;
Abstract
A series of 3,5-diphenyl-4(1H)-pyridazinones are synthesized by a two-step process, both steps of which are new. In the first step, a phenylglyoxyloyl halide is reacted with a styrylamine in the presence of a base to form a 1-amino-2,4-diphenyl-1-buten-3,4-dione. In the second step, the enaminoketone formed in the first step is reacted with hydrazine or an alkylhydrazine to form the pyridazinone. Both steps of the reaction proceed in good yields at temperatures in the range of from about 0.degree. C. to about 40.degree. C. in the common reaction solvents.