The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 1977
Filed:
Apr. 29, 1975
Applicant:
Inventors:
Luciano Re, Rome, IT;
Piergiorgio Zappelli, Monterotondo, IT;
Assignee:
Snam Progetti S.p.A., Milan, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ;
U.S. Cl.
CPC ...
536 28 ; 195 52 ; 536 29 ;
Abstract
Nicotinamide 6-(2-hydroxy-3-carboxy-propylamino) purine dinucleotide is prepared by reacting nicotinamide-adenine-dinucleotide with 3,4 epoxybutanoic acid in the presence of perchloric acid to prepare an intermediate wherein the adenine nucleus is alkylated in the N.sub.1 position. That intermediate is subjected to chemical reduction of the nicotinamide ring, followed by rearrangement to yield the end product wherein the amino group in position 6 of the adenine ring is alkylated.