The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 1977
Filed:
Oct. 18, 1974
Applicant:
Inventors:
Assignee:
Sankyo Company Limited, , JA;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07G / ;
U.S. Cl.
CPC ...
536 17 ; 424180 ;
Abstract
New derivatives of the antibiotic butirosin A having the formula: ##STR1## in which R is a radical of formula (II): ##STR2## and pharmaceutically acceptable acid addition salts thereof. The butirosin A derivatives of formula (I) can be prepared by reduction of a 5'-azido compound having the formula (III): ##STR3## in which R' is the same groups R or a group which, on reduction, gives a group of formula (II). The butirosin A derivatives of general formula (I) and pharmaceutically acceptable acid addition salts thereof are active against a broad spectrum of Gram-positive and Gram-negative bacteria, including some butirosin-resistant strains.