The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 1977

Filed:

Sep. 08, 1975
Applicant:
Inventors:

Robert James Collins, Portage, MI (US);

Charles E Coverdale, Portage, MI (US);

Assignee:

The Upjohn Company, Kalamazoo, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424325 ;
Abstract

Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen or lower alkyl, R.sub.3 represents lower alkyl and A is a monovalent group of formula: ##STR2## wherein Y is hydrogen or the acyl radical of a hydrocarbon carboxylic acid having from 2 to 18 carbon atoms, inclusive, are employed as anticonvulsants in treating mammals, including humans. Novel compounds within the scope of the above formula are also disclosed, wherein R.sub.1 is specifically lower alkyl and provided that R.sub.1 is located in a position ortho or meta to the substituent group A when R.sub.2 is hydrogen. Disclosed also are novel intermediate compounds for preparing the above-described novel compounds of the invention, which correspond thereto but wherein the group A is replaced by a nitro-group.


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