The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 1976
Filed:
Sep. 10, 1974
Applicant:
Inventor:
Barend H Hofstee, Palo Alto, CA (US);
Assignee:
Palo Alto Medical Research Foundation, Palo Alto, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07G / ;
U.S. Cl.
CPC ...
260-8 ; 195 63 ; 195 / ; 195 68 ; 195127 ; 195D / ; 210 24 ; 2601 / ;
Abstract
Separation of proteins from one another by passing an aqueous solution of a mixture of proteins through two or more bodies of matrices each having hydrophobic ligands covalently attached to it, the order of hydrophobicity being such that the protein mixture comes into contact with a first body having the least hydrophobic ligands, then with a second body having more hydrophobic ligands, etc., whereby the most highly hydrophobic proteins are adsorbed on the first (least hydrophobic) matrix, etc. in order of increasing hydrophobicity of the matrices and decreasing hydrophobicity of the proteins in the mixture.