The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 1976

Filed:

Apr. 04, 1973
Applicant:
Inventors:

Peder Bernhard Berntsson, Vastra Frolunda, SW;

Arne Elof Brandstrom, Goteborg, SW;

Enar Ingemar Carlsson, Kungsbacka, SW;

Stig Ake Carlsson, Molnlycke, SW;

Lars Ek, Onsala, SW;

Benny Roger Samuelsson, Pixbo, SW;

Sven Erik Sjastrand, Kungsbacka, SW;

Gert Christer Strandlund, Molndal, SW;

Bengt Arne Ablad, Goteborg, SW;

Assignee:

Aktiebolaget Hassle, Goteborg, SW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ;
U.S. Cl.
CPC ...
424330 ; 2605707 ;
Abstract

Ortho-para-substituted phenoxy-hydroxypropylamines having the general formula ##STR1## and pharmaceutically acceptable, non-toxic acid addition salts thereof, wherein R.sup.1 is alkyl or hydroxy alkyl, R.sup.2 is alkoxyalkyl, alkylthioalkyl, alkoxycarbonylaminoalkyl, or alkoxyalkoxy, and R.sup.3 is halogen, alkyl, alkenyl, alkinyl, alkoxymethyl, or alkoxy are disclosed as are methods for their preparations; Pharmaceutical preparations are prepared whose active ingredients include at least one of the newly discovered phenoxy-hydroxypropylamine compounds. Therapeutically effective doses of these preparations selectively block the .beta.-receptors of the heart making them useful in treating heart diseases in animals including humans.


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