The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 1976
Filed:
Jan. 29, 1975
Ceskoslovenska akademie ved, Prague, CS;
Abstract
The invention relates to a method for preparation of hydrophilic cation exchangers by a chemical modification of crosslinked copolymeric gels containing reactive hydroxyl groups and based on hydroxyalkyl, oligoglycol or polyglycol acrylates and methacrylates and hydroxyalkylacrylamides or hydroxyalkylmethacrylamides. The modification is carried out in reactions of hydroxyl groups with halogenalkane acids and their derivatives, anhydrides and halides of dicarboxylic acids or carbodiimides. If the modification agent contains several reactive groups, the remaining functional groups after modification may be allowed to react with dicarboxylic, polycarboxylic, hydroxycarboxylic or aminocarboxylic acids, or phosphoric or sulfuric acid, halogenoepoxides, diepoxides or polyepoxides. The hydroxyl groups can be also modified by oxidation to carboxylic groups by common oxidants. The gels used for modification may also contain alkoxide reactive groups and they have generally the homogeneous, semiheterogeneous or macroporous character. The ion-exchanging gels prepared in this way are suitable for sorption and chromatographic separations, especially for separation of sensitive biological materials.