The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 1976

Filed:

Mar. 04, 1975
Applicant:
Inventors:

Tetsuo Hiraoka, Tokyo, JA;

Yukio Sugimura, Tokyo, JA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ;
U.S. Cl.
CPC ...
2602391 ; 2602 / ; 424246 ; 424271 ;
Abstract

A process for preparing a 7.beta.-acylamino-7.alpha.alkoxycephalosporin or 6.beta.-acylamino-6.alpha.-alkoxypenicillin which comprises either (a) reacting a 7.beta.-(.alpha.'-halogeno or .alpha.'-hydroxyacylamino)cephalosporin or 6.beta.-(.alpha.'halogeno or .alpha.'-hydroxyacylamino)penicillin with a halogenating agent to give a .alpha.-halogeno-iminohalide, reacting the latter compound with an equimolar amount of an alkali metal alkoxide in the presence of one equivalent amount of a base to give a 7.alpha.-alkoxyketeneimine and subjecting the latter compound to hydration; or (b) reacting the 7.beta.-(.alpha.'-halogeno or .alpha.'hydroxyacylamino)cephalosporin or 6.beta.-(.alpha.'-halogeno or .alpha.'-hydroxyacylamino) penicillin with the halogenating agent to give the .alpha.-halogeno-iminohalide, reacting the latter compound with two equimolar amounts of the alkali metal alkoxide in the presence of one equivalent amount of the base to give a dialkoxyimino compound, reacting the latter compound with a halogeno-silyl compound or an acid and treating the resulting product with water. The final products are useful as antibacterial agents or intermediates thereof.


Find Patent Forward Citations

Hiraoka, Tetsuo. (1976). Process for preparing 7.beta.-acylamino-7.alpha.-alkoxycephalosporins or (U.S. Patent No. 3960845). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/3960845

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