The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 1976
Filed:
Jul. 02, 1974
Applicant:
Inventors:
Brian Burton, Ruislip, EN;
William Graham, Gerrards Cross, EN;
Assignee:
Glaxo Laboratories Limited, Greenford, EN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
2602 / ; 424246 ;
Abstract
7.beta.-Amino-3-methylceph-3-em-4-carboxylic acid is converted to cephalexin in high yield and relatively uncontaminated with unreacted 7.beta.-amino-3-methylceph-3-em-4-carboxylic acid if it is silylated prior to acylation with phenyl glycyl chloride hydrochloride and if the acylation reaction is conducted in dimethylformamide at low temperature in the presence of certain weak tertiary nitrogen bases.