The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 1976
Filed:
Jun. 05, 1974
Alois Piskala, Prague, CS;
Frantisek Sorm, Prague, CS;
Ceskoslovenska akademie ved, Prague, CS;
Abstract
Process for preparing 2',3',5'-tri-0-acetyl-6-azauridine having the following formula ##SPC1## Which comprises reacting a crude anomeric mixture of methyl D-ribofuranosides having the formula ##SPC2## With anhydrous hydrogen chloride or anhydrous hydrogen bromide in the presence of acetic anhydride and acetic acid to thereby form the corresponding 2,3,5-tri-0-acetyl-D-ribofuranosyl halide having the formula ##SPC3## Wherein X is chloro or bromo, reacting the halide of formula III with 3,5-bis-trimethylsilyloxy-1,2,4-triazine having the following formula ##SPC4## In the presence of an inert solvent and a mercuric halide and recovering the 2',3',5'-tri-0-acetyl-6-azauridine.