The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 1976
Filed:
May. 20, 1975
Carlton E Turner, Oxford, MS (US);
John C Craig, Jr, Oxford, MS (US);
The University of Mississippi, University, MS (US);
Abstract
A compound prepared from the extract of Xanthium strumarium (cockleburr) characterized by being a white crystalline glycoside having a decomposition point of 278.degree.-279.degree.C.; a molecular formula of C.sub.31 H.sub.48 O.sub.24 S.sub.2, the aglycone portion of the molecule having a molecular formula of C.sub.19 H.sub.28 O.sub.4 ; substantially no ultraviolet absorption above 200 m.mu.; infrared spectrum showing hydrogen bonded OH absorption, 3440 cm.sup.-.sup.1 ; C--H stretch, 2940 cm.sup.-.sup.1 ; carbonyl stretch, 1735 cm.sup.-.sup.1 ; C--O stretch, 1250 cm.sup.-.sup.1 ; and other absorptions at 1640; 1460; 1380; 1040; 1000; 900; and 800 cm.sup.-.sup.1 ; a nuclear magnetic resonance spectrum in deuterium oxide showing a broad absorption at 304, 230, 162, 134, 92 and 58 cps relative to external tetramethylsilane standard; and the mass spectrum of the silylated derivative gives a mass fragment of 952 amu. Hypoglycemic compositions consisting essentially of the foregoing described compound prepared from cockleburrs in admixture with a non-toxic, pharmaceutically-acceptable carrier. A method of reducing blood sugar levels in animals comprising administering a therapeutically effective concentration of the inventive compound in a pharmaceutically suitable carrier intravenously, orally, intraperitoneally and intramuscularly. The method of preparing a hypoglycemic pharmacologically active therapeutic compound from cockleburrs (Xanthium strumarium).